Researchers at Minia University Hospital in Minia, Egypt recently published a study in the European Journal of Obstetrics & Gynecology and Reproductive Biology. The study shows an all-natural treatment works just as well as prescription clomiphene citrate at inducing ovulation and other positive changes to support conception in patients with polycystic ovary syndrome (PCOS).
Participants were given either cimicifuga racimosa extract or clomiphene citrate starting day 2 of the cycle. Treatment continued for three cycles. Researchers noted FSH (follicle-stimulating hormone), LH (luteinizing hormone) and the ratio of FSH/LH. Progesterone, rate of pregnancy and thickness of the uterine lining were also noted.
Conclusion: Cimicifuga racimosa extract was just as successful at stimulating ovulation at clomiphene citrate. Doctors may want to assess the risks versus rewards of clomiphene citrate when choosing the best treatment protocol for a patient. Overall pregnancy rate was slightly higher in the cimicifuga racimosa group, though the improvement was small and considered clinically insignificant.
Kamel HH. Role of phyto-oestrogens in ovulation induction in women with polycystic ovarian syndrome. Eur J Obstet Gynecol Reprod Biol. 2013 Jan 21. pii: S0301-2115(13)00007-9. doi: 10.1016/j.ejogrb.2012.12.025.