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late ovulation and clomid

Dr. Amos, I am 40 years old and my husband and I have been TTC since January. I have always had longer than average cycles of irregular length. Despite this, 2 1/2 years ago I conceived the first time we tried, I miscarried early, then conceived again the first time we tried, and had our daughter (now 19 months old). I have only been charting temps for 3 cycles now, but my ovulation has been on CD26, CD21, and so far this month I'm on CD 21 and haven't ovulated yet.

Is it unusual that I was able to conceive so easilly 2 years ago but not now? I am also wondering if late ovulation is an indication for clomid. If that is something that might help me, would my regular OB prescribe it or is it something I would see an RE about?

Thank you, -Cailin

bp's picture
982 Posts
By: bp On: Oct 8, 2006  4:37PM

my regular ob will perscribe to me too. (if im not prego after this cycle)

good luck

MomOfSuperheros's picture
2689 Posts
By: MomOfSuperheros On: Oct 7, 2006  7:16PM

Just wanted to let you know that my regular OB prescribes clomid, but for a trial only (3-4 cycles), then will refer to an RE. He'll refer sooner but leaves it up to his pateints on what they want to do. So, soem OBs will prescribe it... I was just prescribed clomid for a combination of things: PCOS (anovulatory) and when i do ovulate it's usually LATE in my cycle (well past cd 20)...so my doc thinks it will benefit me for a more properly timed O (like Dr. A just mentioned) but also a more predictable O.

HTH? For sure mention it to your regular OB as a starting point...

Dr-Amos's picture
1431 Posts
By: Dr-Amos On: Oct 6, 2006  9:44AM

There is not complete agreement on what it means if you ovulate "too early" or "too late." "Too early" would be ovulation on cycle day 10 or earlier and "too late" would be ovulation on cycle day 20 or later. It's possible to get pregnant if you regularly ovulate late in the menstrual cycle, it happens all the time. But when you ovulate late your chances of getting pregnant are somewhat reduced because there are several problems with late ovulation:

You have fewer chances of ovulating over a given time period. For example, if you ovulate on CD 25, and your cycle last 39 days, then you ovulate only 9 times a year or so, as compared with someone with a 28-day cycle who ovulates 13 times per year. With too-late or too-early ovulation you may be releasing eggs that have not matured properly. Improperly matured eggs are not as good for fertilization and implantation as eggs that have matured properly. The reproductive system (hormone levels) is not in sync when eggs mature late, thus further decreasing the chance of pregnancy. The lining of the uterus (endometrium) may not be ready for implantation when too much time has passed since the last menstrual period. The egg may have become fertilized but the blastocyst (the fertilized egg) arrives in the uterus late and it cannot implant properly because the lining is not appropriate. Late ovulation would require that your doctor first do some tests and depending on them you *may* be a candidate for Clomid.

Amos Grunebaum, MD New York, NY