What is DHEA-S?
DHEA-S (dehydroepiandrosterone sulfate) is excreted by the adrenal glands. Blood tests are ordered if female patients show signs of excessive masculinity or if an adrenal tumor is suspected. One of the causes of altered DHEA-S levels is polycystic ovary syndrome.

DHEA-S testing can also be ordered in men and children. Abnormal DHEA-S values in children could be associated with congenital adrenal hyperplasia or precocious puberty (very early puberty).

Normal Value Range

  • Negative Pregnancy Adult: 48 to 252* mg/dL or 1.3 to 6.8* µmol/L
  • Pregnancy Trimester One: 74 to 611 mg/dL or 2 to 16.5 µmol/L
  • Pregnancy Trimester Two: 33 to 289 mg/dL or 0.9 to 7.8 µmol/L
  • Pregnancy Trimester Three: 30 to 241 mg/dL or 0.8 to 6.5 µmol/L

*Values measured for women before menopause.    

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