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Uric Acid (Serum) During Pregnancy

What is Uric Acid?
Patients with high levels of uric acid may experience joint pain, which is also a symptom of gout. Doctors may order a uric acid blood test to verify a gout diagnosis. If uric acid levels are higher than normal, patients are more likely to suffer from kidney stones. Radiation and chemotherapy can increase uric acid levels in blood, so this blood test is generally included in regular blood screenings for cancer patients.

Normal Value Range

  • Negative Pregnancy Adult: 2.5 to 5.6 mg/dL or 149 to333 µmol/L
  • Pregnancy Trimester One: 2 to 4.2 mg/dL or 119 to 250 µmol/L
  • Pregnancy Trimester Two: 2.4 to 4.9 mg/dL or 143 to 292 µmol/L
  • Pregnancy Trimester Three: 3.1 to 6.3 mg/dL or 184 to 375 µmol/L

What does overproduction of uric acid mean with regards to preeclampsia?
An overproduction of uric acid occurs when there is excessive breakdown of cells, or a kidney problem with the inability of the kidneys to excrete uric acid. Preeclampsia is a disease that can affect different organs, including the kidneys. It's not that the uric acid in and of itself is harmful, but an increase in the serum uric acid could be a sign of increased kidney disease and a worsening of preeclampsia. As preeclampsia gets worse, the uric adic can also increase. That's why doctors usually use the serum uric acid as one measure to gauge severity of preeclampsia.

< Laboratory Values During Pregnancy

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