Primary amenorrhea is diagnosed when a woman does not get her period by the age of 14 or 16 years of age.
Primary amenorrhea is defined as:
Secondary amenorrhea is defined as:
There are 3 main reasons for primary amenorrhea:
This is the congenital absence of a vagina. Women without vagina do not menstruate.
Androgen Insensitivity Syndrome
When the body lacks the ability to respond to male hormones there is the appearance of a female despite having a male chromosomal pattern and gonadal production of male hormones. However, the person does not have a uterus or periods, pubic and axillary hair are scant, and testosterone levels are in the male hormone range.
Turner syndrome is a common genetic condition in which where one of the X chromosomes is missing, and the person has 45 (45,X) instead of 46 chromosomes (46,XY or 46, XX). This is usually associated with absent menses and failure to develop ovaries. Without ovaries, you will develop as a female but never undergo puberty.
Other causes of primary amenorrhea
When there is primary amenorrhea, the doctor's first step would be to do a pregnancy test, then test blood for the hormone FSH. If this is elevated, a chromosomal evaluation is in order. A careful physical examination, transvaginal ultrasound and FSH blood test can help your physician narrow the possibilities.