Conceiving w/ late ovulation -- increased risk of birth defects?

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Conceiving w/ late ovulation -- increased risk of birth defects?

Hello Dr. Grunebaum,

Does conceiving with late ovulation lead to an increased risk of birth defects? I have PCOS, and my menstrual cycles are irregular, varying anywhere from 28 to 45 days. This cycle, I ovulated on day 25, and I'm worried about there being a heightened risk of birth defects if I conceived this cycle. I've read some information/studies indicating that longer follicular phases are associated with a significantly increased risk of birth defects and miscarriage due to egg quality and/or endometrial lining quality being poor when ovulation is delayed. Could you please inform me of your thoughts on this issue? I am very worried and upset, and I hope you can shed some light on this issue.

Your assistance would be greatly appreciated. Thank you very much for everything you do.


There is no scientific evidence that late ovulation increases fetal malformations. It increases the risk of a miscarriage or implantation failure but not the risk of a fetal malformation.

Thank you, Doctor. I really appreciate it.