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Protein Intake and Ovulatory Infertility

    OBJECTIVE: The objective of the study was to evaluate whether intake of protein from animal and vegetable origin is associated with ovulatory infertility.

    STUDY DESIGN: A total of 18,555 married women without a history of infertility were followed up as they attempted a pregnancy or became pregnant during an 8 year period. Dietary assessments were related to the incidence of ovulatory infertility.

    RESULTS: During follow-up, 438 women reported ovulatory infertility. The multivariate-adjusted relative risk (RR) (95% confidence interval [CI]; P for trend) of ovulatory infertility comparing the highest to the lowest quintile of animal protein intake was 1.39 (1.01 to 1.90; 0.03). The corresponding RR (95% CI; P for trend) for vegetable protein intake was 0.78 (0.54 to 1.12; 0.07). Furthermore, consuming 5% of total energy intake as vegetable protein rather than as animal protein was associated with a more than 50% lower risk of ovulatory infertility (P =.007).

    CONCLUSION: Replacing animal sources of protein with vegetable sources of protein may reduce ovulatory infertility risk.

     

    Chavarro JE, Rich-Edwards JW, Rosner BA, Willett WC.
    Am J Obstet Gynecol. 2008 Feb;198(2):210.e1-7.