What is 17-Hydroxyprogesterone?
The blood test for 17-hydroxyprogesterone (17-OHP) is often used as a screening or monitoring tool for patients with congenital adrenal hyperplasia. In some cases the blood test is ordered as part of a series of tests to rule out certain medical conditions. Cortisol production is associated with 17-OHP; the precursor. The amount of 17-OHP in the blood is directly related to the amount of cortisol in the body. Cortisol is a hormone that naturally increases during times of stress, but it is a healthy hormone responsible for blood pressure control and immune system regulation.

Normal Value Range

  • Female (Menstruation): (Follicular) 20 to 100, (Mid-Cycle) 100 to 250, (Luteal) 100 to 500 ng/dL or (Follicular) 0.6 to 3, (Mid-Cycle) 3 to 7.5, (Luteal) 3 to 15 nmol/L
  • Pregnancy Trimester One: 172 to 941 ng/dL or 5.2 to 28.5 nmol/L
  • Pregnancy Trimester Two: 172 to 941 ng/dL or 5.3 to 28.5 nmol/L
  • Pregnancy Trimester Three: 512 to 2772 ng/dL or 15.5 to 84 nmol/L

< Laboratory Values During Pregnancy