What is Ceruloplasmin?
Ceruloplasmin is a protein that contains copper. Blood tests for ceruloplasmin are often ordered if patients show signs of Wilson Disease. Common symptoms include jaundice, tremors, fatigue and anemia.

High levels of ceruloplasmin may also be measured if the patient currently has an infection, damage to body tissues or inflammation.

Normal Value Range

  • Negative Pregnancy Adult: 25 to 26 mg/dL or 250 to 630 mg/L
  • Pregnancy Trimester One: 30 to 49 mg/dL or 300 to 490 mg/L
  • Pregnancy Trimester Two: 40 to 53 mg/dL or 400 to 530 mg/L
  • Pregnancy Trimester Three: 43 to 78 mg/dL or 430 to 780 mg/L

Levels higher than normal can be measured if leukemias, carcinomas, lupus, pregnancy, rheumatoid arthritis, Hodgkin disease, estrogen exposure, biliary cirrhosis (primary) or copper intoxication is present.

Lower than normal levels could be a sign of Menkes kinky hair syndrome, Wilson disease, malabsorption, nephrotic syndromes and liver disease (advanced).

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