What is Mean Platelet Volume?

The mean platelet volume is nothing more than a measurement of the average platelet size. The number of platelets in a blood samples is also noted during the test. Depending on the volume of the platelet/ platelet count, different possible conditions could be name

For a pregnant woman, high platelet volume with a low platelet count is often what the obstetrician is looking for if symptoms of preeclampsia are present.

Normal Value Range

  • Negative Pregnancy Adult: 6.4 to 11 µm3 or 6.4 to 11 fl
  • Pregnancy Trimester One: 7.7 to 10.3 µm3 or 7.7 to 10.3 fl
  • Pregnancy Trimester Two: 7.8 to 10.2 µm3 or 7.8 to 10.2 fl
  • Pregnancy Trimester Three: 8.2 to 10.4 µm3 or 8.2 to 10.4 fl

Results of the Mean Platelet Volume test are a bit confusing as size and number must be taken into consideration.

High Volume/Low Count means platelets are being destroyed. Sepsis and preeclampsia can both cause high platelet volume with low platelet count.

Low Volume/Low Count means not enough platelets are being produced. Anemia and certain drugs can reduce the production of platelets.

Low Volume/High Count could be indicative of inflammation, infection or malignancy associated with thrombocytosis.

High Volume/Normal Count could be an indicator of leukemia or hyperthyroidism.

Low Volume/Normal Count is typical of renal failure.

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