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Clomid With a Missed Period and a Negative Pregnancy Test

    As an Ob Gyn I am usually dismayed how many women take clomiphene citrate (Clomid) and don't know what it does and how take it.

    So let me be very clear: The most important thing to know about clomiphene citrate (Clomid) is that it is a medication to induce ovulation. Nothing else. Ovulation, the BIG O. Not fertility. Not necessarily pregnancy. Ovulation.

    Clomiphene is not a fertility medication. It does just get you pregnant in and by itself. All that clomiphene does is that it is supposed to make you ovulate. Obviously, you can only get pregnant if you first ovulate and that is why women take clomiphene, but first things first: Clomid is supposed to make you ovulate.Getting pregnant is much more complicated.

    If you don't get pregnant on clomiphene that doesn't mean it did not work. It may have worked and it may have made you ovulate but pregnancy in and by itself is not the only measure that clomiphene worked.

    Getting pregnant is more complicated than just ovulation. In order to get pregnant the following has to happen:

    1. You need to ovulate and your egg quality has to be good
    2. He has to have enough and good enough sperms
    3. You fallopian tubes must be open for sperms and egg to meet

    So how do you know that Clomid has worked? (Hint: Read above. What is is supposed to do? Make you ovulate). You ovulate on clomiphene that means it worked. You did not ovulate it did not work. Yes, it's that simple. In fact, not every woman will ovulate on clomiphene and many women who ovulate will not get pregnant. With or without clomiphene.

    Obviously if you get pregnant then you know that you did ovulate, but let's not get ahead of this.

    Women who take clomiphene (Clomid) must first know if they ovulate or not.
    So let's start at the beginning: You take clomiphene for 5 days (usually cycle days 5-9 but you can start taking clomiphene as early as cycle day 2). Ovulation is then supposed to happen about 5-9 days later. Don't know exactly when? Check our interactive Clomid Calculator.
    How do you know you ovulate? There are several ways to find out if and when you ovulate:

    1. Calculation: Ovulation and Fertility Charting and Calculator
    2. Temperature Charting
    3. Cervical Mucus Changes
    4. Ovulation Pain: Mittelschmerz
    5. OPK Ovulation Predictor Kit
    6. Blood Progesterone Test
    7. Ultrasound Exams of Ovaries

    Read more about typical Ovulation Symptoms HERE.

    Your menstrual period and ovulation

    With or without clomiphene, your menstrual period is supposed to come 14 days after ovulation. There are 3 scenarios you must know about when trying to get pregnant:

    Scenario#1: You ovulate and did NOT get pregnant: Your menstrual period will arrive about 14 days after the day of ovulation.
    Scenario#2: You ovulate and get pregnant. Your menstrual bleeding, your period will not arrive 15+ days after the day of ovulation.
    Scenario#3: You did NOT ovulate. If you don't ovulate then you will usually not get a regular period. You may bleed or spot irregularly but it's not a menstrual period.  

    Our recommendation

    Before you start taking clomiphene to induce ovulation do the following:

    1. A cycle day 3 FSH tro make sure your eggs have a good enough quality
    2. A sperm count
    3. Make sure your fallopian tubes are open.

    No matter how well clomiphene works to make you ovulate, you will have difficulties getting pregnant unless you have good enough quality eggs, his sperms are OK and your tubes are open.