Researchers at Aristotle University used a participant pool of 240 menopausal women to study the impact of endometriosis on assisted reproductive outcome. One-half the study population was diagnosed with endometriosis with the other half showing no signs of the condition. Sibling oocytes were used for the study. The sibling oocyte pairs were split among the two groups of menopausal women. The idea of the study was to investigate the impact of endometriosis on assisted outcome in menopausal women with endometriosis.

Data reported an implantation rate of 23.81% in the endometriosis group compared to an implantation rate of 31.48% in the control group. Pregnancy rates in the endometriosis and control groups were 45% and 58.33%, respectively.

Infertility is an issue in women with endometriosis because of oocyte quality and affected implantation, but problems with pregnancy extend to menopausal women using donor eggs as revealed in the sibling oocyte study.

Source: Prapas Y, Goudakou M, Matalliotakis I, Kalogeraki A, Matalliotaki C, Panagiotidis Y, Ravanos K, Prapas N.History of endometriosis may adversely affect the outcome in menopausal recipients of sibling oocytes. Reprod Biomed Online. 2012 Aug 8. pii: S1472-6483(12)00469-5. doi: 10.1016/j.rbmo.2012.07.020.