hCG Levels and Twins

  • early pregnancy hcg and hormone levels

I am 18 DPO and my serum hCG is 556. Could this mean I have twins?

A serum hCG of 556 mIU/mL at 18 DPO is normal both for one or two fetuses. You could have twins, but you can't really tell from the serum hCG value alone. At 18 DPO the serum hCG for singletons is normally between about 70 and 750 mIU/mL, and for twins it can be between 200 and about 1750 mIU/ml.

Twins When HCG Increasing Too Fast

In most pregnancies, the normal hCG rises is at least 60% over 48 hours. In twins it may rise much more, but it's not possible to diagnose a twin pregnancy just from the hCG levels alone. the hCG can rise mnanyfold even without twins.

  1. In most normal pregnancies at hCG levels below 1,200 mIU/ml the hCG level usually doubles every 48-72 hours and it normally increases by at least 60% every two days.
  2. In early pregnancy a 48-hour increase of hCG by 35% can still be considered normal
  3. As your pregnancy progresses, the HCG level increase slows down significantly.
  4. Between 1,200 and 6,000 mIU/ml serum, the hCG level usually takes 72-96 hours to double
  5. Above 6,000 mIU/ml, the human chorionic gonadotropin hCG levels often takes over four or more days to double
  6. In general, when the HCG level reached 7200 mIU/ml, a yolk sac should be seen.
  7. At an HCG level greater than 10,800 mIU/ml there should be a visible embryo with a heartbeat

Check more hCG information HERE

Check the hCG Calculator HERE

There is no sufficient scientific evidence that with twins there is always a faster-than-usual rise in hCG. Normal hCG values can vary up to 20 times in normal pregnancies. Variations in hCG increases are not necessarily a sign that the pregnancy is abnormal or that there are two or more fetuses. 

  NORMAL TWIN PREGNANCIES NORMAL SINGLE PREGNANCIES
Day after LH or HCG Average High Low Average High Low
mIU/ml mIU/ml mIU/ml mIU/ml mIU/ml mIU/ml
14 68 313 56 48 119 17
15 88 159 26 59 147 17
16 146 803 112 95 223 33
17 154 542 52 132 429 17
18 360 1760 200 292 758 70
19 499 2509 215 303 514 111
        522 1690 135
21 963 5859 631 1061 4130 324

< hcG Levels and hCG Level Chart by Week

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