HPV during pregnancy has not been connected with pregnancy complications such as miscarriage or premature labor.

Genital warts can proliferate and become friable during pregnancy; due to the altered immunity as well as increased blood supply HPV types 6 and 11 can, rarely, cause papillomatosis in infants and children. The route of transmission (Transplacental, perinatal, or postnatal) is not completely understood. There is no recommendation to do a cesarean delivery just to prevent transmission of HPV infection to the newborn. In rare instances caesarean delivery may be indicated for women with genital warts if the pelvic outlet is obstructed or if vaginal delivery would result in excessive bleeding.

Treatment during pregnancy requires some special considerations. Imiquimod, podophyllin and podophyllotoxin should not be used during pregnancy. Appropriate treatments with external genital warts during pregnancy include cryotherapy, TCA or surgical removal and laser ablation.

There is no reason to avoid pregnancy just because you have a history of genital warts. Human papilloma virus (HPV), the virus responsible for genital warts, Condylomata acuminata or venereal warts, is a very contagious sexually transmitted disease, which is spread by sexual contact with an infected partner. Approximately two-thirds of people who have regular sexual contact with a partner with genital warts for three months will become infected with HPV. So if you have had regular, unprotected intercourse since you got married, there is really no need to use condoms now. Chances are that your partner has already become infected. But you should be concerned about yourself and get a Pap smear before you try to conceive. HPV does not interfere with a woman's ability to get pregnant. Nor does it prevent her from having a healthy and successful pregnancy. Studies have shown that women infected with HPV have the same proportion of healthy babies as women who test negative for HPV.