uterus anomalies bicornuate uterus

What is a Mullerian or uterine anomaly?

Sometimes the uterus fails to develop correctly. This usually happens when the fetus is inside the uterus, before the baby is born, and it's called as a "congenital uterine anomaly."

Uterine anomalies are thought to be quite rare and often they cause no problems and remain undetected. However, when there is a uterine anomaly then problems in pregnancy are quite frequent. In case of repeated, unexplained miscarriage and/or premature birth, a uterine anomaly may be suspected. Uterine anomalies can be diagnosed accurately, and often can be corrected making it possible for a woman to have a baby. A prolapsed uterus or a tipped uterus is not a uterine abnormality but they are considered uterine conditions rather than abnormalities or anomalies. Uterine anomalies are often categorized as follows:

I. Hypoplasia/Agenesis – a small or underdeveloped uterus

II. Unicornuate uterus – a banana shaped uterus with a single horn and sometimes a rudimentary second horn.

III. Uterus didelphys – a double uterus that may also be associated with a double cervix and/or vagina.

IV. Bicornuate uterus - A uterus which has 2 horns

V. Septate uterus – a wall or septum partially or fully divides the uterus into two cavities.

VI. Arcuate uterus - A uterus that has an arc

VII. DES Drug related - characterized by a T-shape

Causes of uterine anomalies

The exact causes for uterine anomalies are not known, but it's generally thought that a combination of genetic and environmental causes are responsible. For example, a particular uterine anomaly characterized by a T-shaped uterus has been found in women whose mothers took the drug diethylstilbestrol (DES) during their pregnancy. Because few women with an irregularly shaped uterus also have close relatives with the same problem, the condition is not thought to run in families.

Incidence of uterine anomalies

An incidence of uterine anomalies as low as 0.1% has been reported. Observations made at the time of delivery indicate an incidence of 2 to 3%. The most common uterine anomalies are the septate and bicornuate and didelphic uteruses. The unicornuate uterus is the least common type.

Pregnancy outcome with bicornuate uterus and other uterine anomalies 

  Live Birth Preterm Birth Ectopic Miscarriage
Arcuate Uterus  66.2% 5.1%   3.6%  20.1%
Uterine Septum  58.1%  10%  1.9%  75.7%
Bicornuate Uterus 62.5%  25%  25%
Didelphic Uterus 68.6%  24.4%  2.3%  20.9%
Unicornuate Uterus 54.2%  43.3%  4.3%  34.4%
Controls  82%  9-12%  2%  10-15%


Raga. Hum Reprod 1997;12:2277
Fedele. Eur J Obstet Gynaecol 1995 
Lin: J Womens Health 2004 


What are the symptoms of a uterus anomaly?

In many cases a uterine anomaly causes no problems and in fact may remain undetected until menstruation begins or pregnancy is attempted. If a uterine anomaly such as bicornuate uterus results in a rudimentary uterine horn with no outlet, menstrual outflow will be obstructed. This can result in pain and/or a mass similar to endometriosis that gets worse during periods. If untreated, blood collects in the uterus and may become infected. A uterine anomaly may also be associated with dyspareunia and reproductive problems. These include: Infertility, ectopic pregnancy, recurrent miscarriage, premature delivery, intrauterine fetal growth restriction, abnormal fetal presentation – breech and transverse lies.

The incidence of reproductive complications depends on the particular type of anomaly. A septate uterus is the anomaly most commonly associated with recurrent spontaneous abortion.

What are the procedures used to diagnose uterine anomalies? 

The following tests and procedures are used to diagnose a uterine anomaly:

  • Pelvic exam
  • Hysterosalpingogram
  • Ultrasound
  • MRI
  • Laparoscopy
  • Hysteroscopy

How do you treat a uterine anomaly?

Many uterine anomalies can be corrected surgically in case of difficulties. Metroplasty is most often used to reshape the uterus. However, surgery is not indicated in every case and it can not be performed on a unicornuate uterus, as there is no way to surgically enlarge a uterus. Cervical cerclage may be performed in some cases to prevent the cervix from dilating prematurely and to increase the fetal survival rate.